Erratum: Regions of homozygosity in three Southeast Asian populations
نویسندگان
چکیده
منابع مشابه
Characterizing genetic variation in three Southeast Asian populations
Singapore is a small island-nation situated at the tip of the Malay Peninsular in Southeast Asia. It existed as a British colony from 1819 to 1959, interspersed by a period of Japanese occupation from 1942 to 1945 during World War II. Throughout its colonial history, Singapore has been the recipient of extensive immigration from various parts of Asia, and the same diversity is still reflected i...
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In a previous study of Southeast Asian genetic variation, we characterized mitochondrial DNAs (mtDNAs) from six populations through high-resolution restriction fragment length polymorphism (RFLP) analysis. Our analysis revealed that these Southeast Asian populations were genetically similar to each other, suggesting they had a common origin. However, other patterns of population associations al...
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The major histocompatibility complex (MHC) containing the classical human leukocyte antigen (HLA) Class I and Class II genes is among the most polymorphic and diverse regions in the human genome. Despite the clinical importance of identifying the HLA types, very few databases jointly characterize densely genotyped single nucleotide polymorphisms (SNPs) and HLA alleles in the same samples. To da...
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BACKGROUND The prevalence of the metabolic syndrome among a number of Asian populations as defined by several current criteria has been increasing rapidly and appears to resemble that among Western populations. METHODS We review 25 surveys of the metabolic syndrome in Asian populations (PR China, Hong Kong, Taiwan, Japan, Philippines, Singapore) that report adequate information published duri...
متن کاملYin yang haplotypes revisited - long, disparate haplotypes observed in European populations in regions of increased homozygosity.
OBJECTIVES Yin yang haplotypes differ at every SNP. A previous study provided striking examples of these haplotypes, but claimed that their distribution across the genome could be attributed to chance. When we studied regions of homozygosity (ROHs) we found haplotypes that tended to differ at several SNPs simultaneously but did not subject this to formal testing. Here, we formally assess whethe...
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ژورنال
عنوان ژورنال: Journal of Human Genetics
سال: 2012
ISSN: 1434-5161,1435-232X
DOI: 10.1038/jhg.2012.51